Episode 2.10 Progesterone for Miscarriage, Epidurals and Infant Outcomes, and the McClintock Effect

In this episode, we discuss the evidence for risks and benefits for progesterone to prevent miscarriage. We also discuss new evidence linking certain types of progesterone to an increased risk of cancer in offspring. Then we discuss new evidence about epidural use and long term neonatal and child outcomes, including risks of autism. We also dive into the McClintock Effect and discuss some lunar related OB myths.

Links Discussed:

Micronized vaginal progesterone to prevent miscarriage: a critical evaluation of randomized evidence

A Randomized Trial of Progesterone in Women with Bleeding in Early Pregnancy

In utero exposure to 17α-hydroxyprogesterone caproate and risk of cancer in offspring

Cochrane: Are progestogen treatments effective in preventing miscarriage?

Association of Epidural Analgesia in Women in Labor With Neonatal and Childhood Outcomes in a Population Cohort

Association Between Epidural Analgesia During Labor and Risk of Autism Spectrum Disorders in Offspring

Association Between Iatrogenic Delivery for Suspected Fetal Growth Restriction and Childhood School Outcomes

Delivery Before 39 Weeks’ Gestation for Suspected Fetal Growth Restriction: More Harm Than Good?]

Do Women Who Live Together Menstruate Together?